Synlett 1993; 1993(1): 23-25
DOI: 10.1055/s-1993-22332
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Intramolecular Ene Approach to the Bicyclic Subunit of Neocarzinostatin Chromophore: Tandem Ene Cyclization-Cycloaromatization Sequence

Koichi Mikami* , Hiroyuki Matsueda, Takeshi Nakai
  • *Department of Chemical Technology, Tokyo Institute of Technology, Meguro-ku, Tokyo 152, Japan
Further Information

Publication History

Publication Date:
19 March 2002 (online)

The first example of 10-(2,4) ene cyclization is described to afford a bicyclic subunit of neocarzinostatin chromophore, which triggers the Bergman cycloaromatization reaction in tandem.

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