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Vet Comp Orthop Traumatol 2016; 29(04): 344-346
DOI: 10.3415/VCOT-15-06-0111
Brief Communication
Schattauer GmbH

Elevated synovial fluid concentration of adenosine triphosphate in dogs with osteoarthritis or sodium urate-induced synovitis of the stifle

Bryan T. Torres
1   Department of Veterinary Medicine and Surgery, College of Veterinary Medicine, University of Missouri, Columbia, MO, USA
,
David A. Jimenez
2   Department of Veterinary Biosciences and Diagnostic Imaging, College of Veterinary Medicine, University of Georgia, Athens, GA, USA
,
Steven C. Budsberg
3   Department of Small Animal Medicine and Surgery, College of Veterinary Medicine, University of Georgia, Athens, GA, USA
› Author Affiliations
Further Information

Publication History

Received: 24 June 2015

Accepted: 15 March 2016

Publication Date:
17 December 2017 (online)

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Summary

Adenosine triphosphate has been shown to stimulate nociceptive nerve terminals in joints. Elevated synovial fluid adenosine tri -phosphate concentrations as well as a correlation between synovial fluid adenosine tri -phosphate concentrations and osteoarthritic knee pain has been demonstrated in humans, but not yet in dogs. This study documented elevated synovial fluid adenosine triphosphate concentrations in the stifles of dogs with secondary osteoarthritis and urate-induced synovitis, as compared to normal stifles.

Keywords

Osteoarthritis - adenosine triphosphate - urate - synovial fluid
 

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