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DOI: 10.1055/a-1333-3951
Latest Trends in the Current Treatment of Proximal Humeral Fractures – an Analysis of 1162 Cases at a Level-1 Trauma Centre with a Special Focus on Shoulder Surgery
Article in several languages: English | deutschAbstract
Background The management of proximal humeral fracture (PHF) is not only complex but ever changing. Published epidemiological data are often dated and do not factor in demographic changes or the latest developments in implant material and surgical techniques.
Aims The primary aim of this study was to evaluate changes in the epidemiology and actual treatment of PHF at a level-1 trauma centre, with a special focus on shoulder surgery.
Hypotheses 1. Between 2009 to 2012 and 2014 to 2017, an increase in complex PHF entities can be observed. 2. In correlation with fracture complexity, an increasing number of comorbidities, especially osteoporosis, can be observed.
Methods Between 2014 and 2017, a total of 589 patients (73% female; mean age: 68.96 ± 14.9 years) with 593 PHFs were treated. Patient records and imaging (XRs and CTs) of all patients were analysed. Fractures with ad latus displacement of a maximum of 0,5 cm and/or humeral head angulation of less than 20° were classified as non-displaced. Patients with displaced fractures were included in the analysis of the therapeutic algorithm. These results were compared to those of a cohort 2009 to 2012 (566 patients, 569 PHFs), which used the same inclusion criteria.
Results The two cohorts showed comparable patient numbers, as well as gender and age distributions. Between 2009 to 2012 and 2014 to 2017, a decrease in 2-part fractures (13.9 to 8.6%) and a simultaneous increase in 4-part fractures (20.4 to 30%), and thus fracture complexity was observed. Further decreases were observed in conservative therapy (27.8 to 20.6%), nail osteosynthesis (10.7 to 2.7%) and anatomic shoulder arthroplasty (5,4 to 1%). Furthermore, there was an increase in the use of locking plate osteosynthesis (43.2 to 56.7%) and reverse shoulder arthroplasty (9 to 18.4%). The general trend shows an increase in surgical therapy between the years (72.2 to 79.4%), as well as an increase in osteoporosis incidence (13 to 20.6%). The greatest numbers of comorbidities were found in 3- and 4-part fractures.
Conclusion There is an increase in both the complexity of fractures and the number of surgically treated fractures between 2009 and 2012. Furthermore, an increase in osteoporosis numbers can be observed. New implants (PEEK, fenestrated screws for cement augmentation) and new surgical techniques (double plating osteosynthesis) were used as a result of increasing fracture complexity. Moreover, reverse total shoulder arthroplasty was used more commonly.
Key words
proximal humerus fracture - reverse shoulder arthroplasty - osteoporosis - CFR-PEEK plate osteosynthesis - dual plate fixationPublication History
Article published online:
02 February 2021
© 2021. Thieme. All rights reserved.
Georg Thieme Verlag KG
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References/Literatur
- 1 Court-Brown CM, Clement ND, Duckworth AD. et al. The changing epidemiology of fall-related fractures in adults. Injury 2017; 48: 819-824 doi:10.1016/j.injury.2017.02.021
- 2 Passaretti D, Candela V, Sessa P. et al. Epidemiology of proximal humeral fractures: a detailed survey of 711 patients in a metropolitan area. J Shoulder Elbow Surg 2017; 26: 2117-2124 doi:10.1016/j.jse.2017.05.029
- 3 Palvanen M, Kannus P, Niemi S. et al. Update in the epidemiology of proximal humeral fractures. Clin Orthop Relat Res 2006; 442: 87-92 doi:10.1097/01.blo.0000194672.79634.78
- 4 Klug A, Gramlich Y, Wincheringer D. et al. Trends in surgical management of proximal humeral fractures in adults: a nationwide study of records in Germany from 2007 to 2016. Arch Orthop Trauma Surg 2019; 139: 1713-1721 doi:10.1007/s00402-019-03252-1
- 5 Jo YH, Lee KH, Lee BG. Surgical trends in elderly patients with proximal humeral fractures in South Korea: a population-based study. BMC Musculoskelet Disord 2019; 20: 136 doi:10.1186/s12891-019-2515-2
- 6 Rikli D, Feissli S, Müller AM. et al. High rate of maintaining self-dependence and low complication rate with a new treatment algorithm for proximal humeral fractures in the elderly population. J Shoulder Elbow Surg 2020; 29: 1127-1135 doi:10.1016/j.jse.2019.11.006
- 7 Handoll H, Brealey S, Torgerson D. et al. The ProFHER (PROximal Fracture of the Humerus: Evaluation by Randomisation) trial – a pragmatic multicentre randomised controlled trial evaluating the clinical effectiveness and cost-effectiveness of surgical compared with non-surgical treatment for proximal fracture of the humerus in adults. Health Technol Assessment 2015; 19: 1-280 doi:10.3310/hta19240
- 8 Launonen AP, Sumrein BO, Reito A. et al. Operative versus non-operative treatment for 2-part proximal humerus fracture: A multicenter randomized controlled trial. PLoS Med 2019; 16: e1002855 doi:10.1371/journal.pmed.1002855
- 9 Sabesan VJ, Lombardo D, Petersen-Fitts G. et al. National trends in proximal humerus fracture treatment patterns. Aging Clin Exp Res 2017; 29: 1277-1283 doi:10.1007/s40520-016-0695-2
- 10 Katthagen J, Dey Hazra R-O, Raschke MJ. et al. Innovationen bei der Behandlung der proximalen Humerusfraktur. Arthroskopie 2019; 32: 28-39 doi:10.1007/s00142-018-0243-5
- 11 Warnhoff M, Lill H, Jensen G. et al. Proximale Humerusfraktur – was sagt die aktuelle Literatur?. Obere Extrem 2019; 14: 9-17 doi:10.1007/s11678-018-0496-7
- 12 Königshausen M, Kübler L, Godry H. et al. Clinical outcome and complications using a polyaxial locking plate in the treatment of displaced proximal humerus fractures. A reliable system?. Injury 2012; 43: 223-231 doi:10.1016/j.injury.2011.09.024
- 13 Ockert B, Braunstein V, Kirchhoff C. et al. Monoaxial versus polyaxial screw insertion in angular stable plate fixation of proximal humeral fractures: radiographic analysis of a prospective randomized study. J Trauma 2010; 69: 1545-1551 doi:10.1097/TA.0b013e3181c9b8a7
- 14 Röderer G, Scola A, Schmölz W. et al. Biomechanical in vitro assessment of screw augmentation in locked plating of proximal humerus fractures. Injury 2013; 44: 1327-1332 doi:10.1016/j.injury.2013.05.008
- 15 Unger S, Erhart S, Kralinger F. et al. The effect of in situ augmentation on implant anchorage in proximal humeral head fractures. Injury 2012; 43: 1759-1763 doi:10.1016/j.injury.2012.07.003
- 16 Hengg C, Nijs S, Klopfer T. et al. Cement augmentation of the proximal humerus internal locking system in elderly patients: a multicenter randomized controlled trial. Arch Orthop Trauma Surg 2019; 139: 927-942 doi:10.1007/s00402-019-03142-6
- 17 Helfen T, Siebenbürger G, Fleischhacker E. et al. Operative treatment of 2-part surgical neck type fractures of the proximal humerus in the elderly: Cement augmented locking plate PHILOS™ vs. proximal humerus nail multiloc® . Injury 2020; 51: 2245-2252 doi:10.1016/j.injury.2020.06.026
- 18 Katthagen JC, Schwarze M, Warnhoff M. et al. Influence of plate material and screw design on stiffness and ultimate load of locked plating in osteoporotic proximal humeral fractures. Injury 2016; 47: 617-624 doi:10.1016/j.injury.2016.01.004
- 19 Ziegler P, Maier S, Stöckle U. et al. The Treatment of Proximal Humerus Fracture Using Internal Fixation with Fixed-angle Plates. Dtsch Arztebl Int 2019; 116: 757-763 doi:10.3238/arztebl.2019.0757
- 20 Schliemann B, Seifert R, Theisen C. et al. PEEK versus titanium locking plates for proximal humerus fracture fixation: a comparative biomechanical study in two- and three-part fractures. Arch Orthop Trauma Surg 2017; 137: 63-71 doi:10.1007/s00402-016-2620-8
- 21 Theopold J, Schleifenbaum S, Müller M. et al. Biomechanical evaluation of hybrid double plate osteosynthesis using a locking plate and an inverted third tubular plate for the treatment of proximal humeral fractures. PLoS One 2018; 13: e0206349 doi:10.1371/journal.pone.0206349
- 22 Theopold J, Marquaß B, Fakler J. et al. The bicipital groove as a landmark for reconstruction of complex proximal humeral fractures with hybrid double plate osteosynthesis. BMC Surg 2016; 16: 10 doi:10.1186/s12893-016-0125-6
- 23 Michel PA, Katthagen JC, Heilmann LF. et al. Biomechanics of Upper Extremity Double Plating. Z Orthop Unfall 2020; 158: 238-244 doi:10.1055/a-0862-6334
- 24 Katthagen JC, Schliemann B, Michel PA. et al. Clinical Application and Outcomes of Upper Extremity Double Plating. Z Orthop Unfall 2020; 158: 227-237 doi:10.1055/a-0862-1070
- 25 Lopiz Y, Alcobía-Díaz B, Galán-Olleros M. et al. Reverse shoulder arthroplasty versus nonoperative treatment for 3- or 4-part proximal humeral fractures in elderly patients: a prospective randomized controlled trial. J Shoulder Elbow Surg 2019; 28: 2259-2271 doi:10.1016/j.jse.2019.06.024
- 26 Sebastiá-Forcada E, Cebrián-Gómez R, Lizaur-Utrilla A. et al. Reverse shoulder arthroplasty versus hemiarthroplasty for acute proximal humeral fractures. A blinded, randomized, controlled, prospective study. J Shoulder Elbow Surg 2014; 23: 1419-1426 doi:10.1016/j.jse.2014.06.035
- 27 Katthagen JC, Grabowski S, Huber M. et al. Epidemiologie und Versorgungsrealität proximaler Humerusfrakturen an einem spezialisierten Level-1 Traumazentrum. Obere Extrem 2016; 11: 112-118 doi:10.1007/s11678-016-0362-4
- 28 Resch H, Tauber M, Neviaser RJ. et al. Classification of proximal humeral fractures based on a pathomorphologic analysis. J Shoulder Elbow Surg 2016; 25: 455-462 doi:10.1016/j.jse.2015.08.006
- 29 Codman EA. The Shoulder. Rupture of the Supraspinatus Tendon and other Lesions in or about the subacromial Bursa. Boston: Thomas Todd; 1934: 313-331
- 30 Bergdahl C, Ekholm C, Wennergren D. et al. Epidemiology and patho-anatomical pattern of 2,011 humeral fractures: data from the Swedish Fracture Register. BMC Musculoskelet Disord 2016; 17: 159 doi:10.1186/s12891-016-1009-8
- 31 Launonen AP, Lepola V, Saranko A. et al. Epidemiology of proximal humerus fractures. Arch Osteoporos 2015; 10: 209 doi:10.1007/s11657-015-0209-4
- 32 Schliemann B, Siemoneit J, Theisen C. et al. Complex fractures of the proximal humerus in the elderly–outcome and complications after locking plate fixation. Musculoskelet Surg 2012; 96 (Suppl. 01) S3-S11 doi:10.1007/s12306-012-0181-8
- 33 Bahrs C, Stojicevic T, Blumenstock G. et al. Trends in epidemiology and patho-anatomical pattern of proximal humeral fractures. Int Orthop 2014; 38: 1697-1704 doi:10.1007/s00264-014-2362-6
- 34 Nguyen TV, Center JR, Sambrook PN. et al. Risk factors for proximal humerus, forearm, and wrist fractures in elderly men and women: the Dubbo Osteoporosis Epidemiology Study. Am J Epidemiol 2001; 153: 587-595 doi:10.1093/aje/153.6.587
- 35 Court-Brown CM, McQueen MM. Global Forum: Fractures in the Elderly. J Bone Joint Surg Am Vol 2016; 98: e36 doi:10.2106/JBJS.15.00793
- 36 Sumrein BO, Huttunen TT, Launonen AP. et al. Proximal humeral fractures in Sweden–a registry-based study. Osteoporos Int 2017; 28: 901-907 doi:10.1007/s00198-016-3808-z
- 37 Erdle B, Izadpanah K, Eberbach H. et al. [Primary fracture protheses and reverse shoulder arthroplasty in complex humeral head fractures: An alternative to joint-preserving osteosynthesis?]. Orthopade 2018; 47: 410-419 doi:10.1007/s00132-018-3570-3
- 38 Osterhoff G, OʼHara NN, DʼCruz J. et al. A Cost-Effectiveness Analysis of Reverse Total Shoulder Arthroplasty versus Hemiarthroplasty for the Management of Complex Proximal Humeral Fractures in the Elderly. Value Health 2017; 20: 404-411 doi:10.1016/j.jval.2016.10.017
- 39 Anakwenze OA, Zoller S, Ahmad CS. et al. Reverse shoulder arthroplasty for acute proximal humerus fractures: a systematic review. J Shoulder Elbow Surg 2014; 23: e73-e80 doi:10.1016/j.jse.2013.09.012
- 40 Knierzinger D, Heinrichs CH, Hengg C. et al. Biomechanical evaluation of cable and suture cerclages for tuberosity reattachment in a 4-part proximal humeral fracture model treated with reverse shoulder arthroplasty. J Shoulder Elbow Surg 2018; 27: 1816-1823 doi:10.1016/j.jse.2018.04.003
- 41 Katthagen JC, Huber M, Grabowski S. et al. Failure and revision rates of proximal humeral fracture treatment with the use of a standardized treatment algorithm at a level-1 trauma center. J Orthop Traumatol 2017; 18: 265-274 doi:10.1007/s10195-017-0457-8
- 42 Barlow JD, Torchia ME, Sanchez-Sotelo J. et al. Locking-plate fixation of proximal humerus fractures in patients over 60 continues to be associated with a high complication rate. J Shoulder Elbow Surg 2019; 28: e213
- 43 Katthagen JC, Lutz O, Voigt C. et al. Cement augmentation of humeral head screws reduces early implant-related complications after locked plating of proximal humeral fractures. Obere Extrem 2018; 13: 123-129 doi:10.1007/s11678-018-0440-x
- 44 Katthagen JC, Ellwein A, Lutz O. et al. Outcomes of proximal humeral fracture fixation with locked CFR-PEEK plating. Eur J Orthop Surg Traumatol 2017; 27: 351-358 doi:10.1007/s00590-016-1891-7
- 45 Padolino A, Porcellini G, Guollo B. et al. Comparison of CFR-PEEK and conventional titanium locking plates for proximal humeral fractures: a retrospective controlled study of patient outcomes. Musculoskelet Surg 2018; 102 (Suppl. 01) S49-S56 doi:10.1007/s12306-018-0562-8
- 46 Laux CJ, Grubhofer F, Werner CML. et al. Current concepts in locking plate fixation of proximal humerus fractures. J Orthop Surg Res 2017; 12: 137 doi:10.1186/s13018-017-0639-3