Recent Advances on High-Order Dipolar Annulations of Donor–Acceptor Cyclopropanes/Cyclobutanes

Abstract

This short review summarizes the recent impressive developments on the high-order dipolar annulations (HODAs) of donor–acceptor cyclopropanes (DACs) and donor–acceptor cyclobutanes (DABs) to afford medium-sized (hetero)cycles.

1 Introduction

2 (3+m) (m > 3) Annulations of Donor–Acceptor Cyclopropanes

2.1 (3+4) Annulations

2.2 (3+5) Annulations

3 (4+m) (m > 2) Annulations of Donor–Acceptor Cyclobutanes

4 Conclusion

Key words

high-order dipolar annulation - donor–acceptor - cyclopropanes - cyclobutanes - cyclization

Publication History

Received: 21 July 2023

Accepted after revision: 16 August 2023

Accepted Manuscript online:
16 August 2023

Article published online:
28 September 2023

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