Antispasmogenic Effect of Rutamarin and Arborinine on Isolated Smooth Muscle Organs

E. Minker; Csilla Bartha; Zsuzsanna Rózsa; K. Szendrei; J. Reisch

doi:10.1055/s-0028-1097316

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Planta Med 1979; 37(10): 156-160
DOI: 10.1055/s-0028-1097316

Research Articles

Antispasmogenic Effect of Rutamarin and Arborinine on Isolated Smooth Muscle Organs

E. Minker¹ , Csilla Bartha¹ , Zsuzsanna Rózsa² , K. Szendrei² , J. Reisch³

¹Institute of Pharmacodynamics, University Medical School of Szeged, Hungary
²Institute of Pharmacognosy, University Medical School of Szeged, Hungary
³Institute of Pharmaceutical Chemistry Wilhelm's University of Westfalia, Muenster, Federal Republic of Germany

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Publication History

Publication Date:
13 January 2009 (online)

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Abstract

The antispasmogenic activity of rutamarin and arborinine isolated and identified from Ruta graveolens, was studied. Both compounds were found to have antispasmogenic effect on isolated smooth muscle organs. Their potency was comparable to that of papaverine, and the duration of the effect was as long as or possibly longer than that of papaverine.

Key Word Index

Rutamarin, Arborinine, Smooth Muscle Organs, Antispasmogenic Effect