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Synthesis 2010(10): 1629-1632
DOI: 10.1055/s-0029-1218723
DOI: 10.1055/s-0029-1218723
PAPER
© Georg Thieme Verlag
Stuttgart ˙ New York
Bromination of Aromatic Compounds Using Ammonium Bromide and Oxone®
Further Information
Received
15 February 2010
Publication Date:
06 April 2010 (online)
Publication History
Publication Date:
06 April 2010 (online)
Abstract
A simple, efficient and mild method for the selective bromination of activated aromatic compounds using ammonium bromide as the source of bromine and Oxone® as the oxidant in methanol or water as solvent is reported. The reaction proceeds at ambient temperature in yields ranging from moderate to excellent without a catalyst.
Key words
bromination - aromatic compounds - ammonium bromide - Oxone® - selectivity
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