From the aerial parts of Decatropis bicolor, heraclenin (1), seselin (2), psoralen (3), imperatorin (4), skimmianine (5), and heraclenol (6), were isolated. This is the first time that coumarin-like compounds are isolated from Decatropis genus. The anti-inflammatory properties of compounds 1–6 were examined against the ear edema in mice produced by TPA. The results suggest that the anti-inflammatory activity of each compound depends of its individual substitution on the aromatic ring rather than the coumarin skeleton itself.
References
1 Aguilar A, Camacho J R, Chino S, Jácquez P, López M E. Hebario Medicinal del Instituto Mexicano del Seguro Social. México; Instituto Mexicano del Seguro 1994: pp. 253
