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DOI: 10.1055/s-0030-1255518
© Georg Thieme Verlag KG Stuttgart · New York
Use of a NOTES closure device for full-thickness suturing of a postoperative anastomotic esophageal leakage
Publication History
submitted 17 February 2010
accepted after revision 15 April 2010
Publication Date:
30 June 2010 (online)
Leakages at surgical anastomoses in the gastrointestinal tract represent a challenging clinical problem. Standard therapy entails conservative or surgical revision of the anastomotic area with high morbidity and mortality up to 30 %. None of the previous endoscopic approaches, which include stenting, endoscopic clip closure, and fibrin glue injection, are sufficiently established for routine clinical use. We report a case of a 68-year-old woman with a postoperative leakage and abscess at the esophagojejunostomy. The defect was closed with two anchor-lock sutures. The patient was able to resume oral food intake 5 days later and made a full recovery with endoscopically documented mucosal healing at the site of the anastomosis. In summary, endoscopic suturing may be a promising approach for the treatment of postoperative leaks that warrants further, controlled investigation.
References
- 1 Junemann-Ramirez M, Awan M Y, Khan Z M, Rahamim J S. Anastomotic leakage post-esophagogastrectomy for esophageal carcinoma: retrospective analysis of predictive factors, management and influence on longterm survival in a high volume centre. Eur J Cardiothorac Surg. 2005; 27 3-7
- 2 Whooley B P, Law S, Murthy S C. et al . Analysis of reduced death and complication rates after esophageal resection. Ann Surg. 2001; 233 338-344
- 3 Khan A Z, Nikolopolous I, Botha A J, Mason R C. Substernal long segment left colon interposition for oesophageal replacement. Surgeon. 2008; 6 54-56
- 4 Parekh K, Iannettoni M D. Complications of esophageal resection and reconstruction. Seminars in thoracic and cardiovascular surgery. 2007; 19 79-88
- 5 Mariette C, Piessen G, Balon J M. et al . Surgery alone in the curative treatment of localised oesophageal carcinoma. Eur J Surg Oncol. 2004; 30 869-876
- 6 Mariette C, Taillier G, Van Seuningen I, Triboulet J P. Factors affecting postoperative course and survival after en bloc resection for esophageal carcinoma. Ann Thorac Surg. 2004; 78 1177-1183
- 7 Matory Y L, Burt M. Esophagogastrectomy: reoperation for complications. J Surg Oncol. 1993; 54 29-33
- 8 Pennathur A, Luketich J D. Resection for esophageal cancer: strategies for optimal management. Ann Thorac Surg. 2008; 85 751-756
- 9 Rodella L, Laterza E, De Manzoni G. et al . Endoscopic clipping of anastomotic leakages in esophagogastric surgery. Endoscopy. 1998; 30 453-456
- 10 Infante M, Valente M, Andreani S. et al . Conservative management of esophageal leaks by transluminal endoscopic drainage of the mediastinum or pleural space. Surgery. 1996; 119 46-50
- 11 Adler D G, McAfee M, Gostout C J. Closure of an esophagopleural fistula by using fistula tract coagulation and an endoscopic suturing device. Gastrointest Endosc. 2001; 54 652-653
- 12 Roy-Choudhury S H, Nicholson A A, Wedgwood K R. et al . Symptomatic malignant gastroesophageal anastomotic leak: management with covered metallic esophageal stents. AJR Am J Roentgenol. 2001; 176 161-165
- 13 Doniec J M, Schniewind B, Kahlke V. et al . Therapy of anastomotic leaks by means of covered self-expanding metallic stents after esophagogastrectomy. Endoscopy. 2003; 35 652-658
- 14 Tuebergen D, Rijcken E, Mennigen R. et al . Treatment of thoracic esophageal anastomotic leaks and esophageal perforations with endoluminal stents: efficacy and current limitations. J Gastrointest Surg. 2008; 12 1168-1176
- 15 Peters J H, Craanen M E, van der Peet D L. et al . Self-expanding metal stents for the treatment of intrathoracic esophageal anastomotic leaks following esophagectomy. Am J Gastroenterol. 2006; 101 1393-1395
- 16 Page R D, Shackcloth M J, Russell G N, Pennefather S H. Surgical treatment of anastomotic leaks after oesophagectomy. Eur J Cardiothorac Surg. 2005; 27 337-343
- 17 Truong S, Bohm G, Klinge U. et al . Results after endoscopic treatment of postoperative upper gastrointestinal fistulas and leaks using combined Vicryl plug and fibrin glue. Surg Endosc. 2004; 18 1105-1108
- 18 Landen S, El Nakadi I. Minimally invasive approach to Boerhaave’s syndrome: a pilot study of three cases. Surg Endosc. 2002; 16 1354-1357
- 19 Fritscher-Ravens A, Cuming T, Jacobsen B. et al . Feasibility and safety of endoscopic full-thickness esophageal wall resection and defect closure: a prospective long-term survival animal study. Gastrointest Endosc. 2009; 69 1314-1320
- 20 Raju G S, Fritscher-Ravens A, Rothstein R I. et al . Endoscopic closure of colon perforation compared to surgery in a porcine model: a randomized controlled trial (with videos). Gastrointest Endosc. 2008; 68 324-332
- 21 Ikeda K, Fritscher-Ravens A, Mosse C A. et al . Endoscopic full-thickness resection with sutured closure in a porcine model. Gastrointest Endosc. 2005; 62 122-129
- 22 Fritscher-Ravens A, Patel K, Ghanbari A. et al . Natural orifice transluminal endoscopic surgery (NOTES) in the mediastinum: long-term survival animal experiments in transesophageal access, including minor surgical procedures. Endoscopy. 2007; 39 870-875
1 J.H. and B.S. contributed equally to this paper.
A. Fritscher-RavensMD
Department of Internal Medicine I
University Hospital Schleswig-Holstein, Campus Kiel
Schittenhelmstrasse 12
24105 Kiel
Germany
Fax: +49-431-5971302
Email: fri.rav@btopenworld.com