Thorac Cardiovasc Surg 2012; 60(05): 360-362
DOI: 10.1055/s-0031-1295565
Short Communication
Thieme Medical Publishers 333 Seventh Avenue, New York, NY 10001, USA.

Low-Volume, Single-Shot Crystalloid Cardioplegia is Safe for Isolated Aortic Valve Replacement

Peter Matt
1   Clinic for Cardiac Surgery Basel, Heart Surgery Center Basel-Bern, Switzerland
*   These authors contributed equally to this work
,
Emilio Arbeleaz
1   Clinic for Cardiac Surgery Basel, Heart Surgery Center Basel-Bern, Switzerland
*   These authors contributed equally to this work
,
Goetz Schwirtz
1   Clinic for Cardiac Surgery Basel, Heart Surgery Center Basel-Bern, Switzerland
,
Thomas Doebele
1   Clinic for Cardiac Surgery Basel, Heart Surgery Center Basel-Bern, Switzerland
,
Friedrich Eckstein
1   Clinic for Cardiac Surgery Basel, Heart Surgery Center Basel-Bern, Switzerland
› Author Affiliations
Further Information

Publication History

12 January 2011

21 July 2011

Publication Date:
29 December 2011 (online)

Abstract

We report our experience with a low-volume (100 mL), single-shot crystalloid cardioplegia (Cardioplexol) in 61 consecutive patients undergoing isolated aortic valve replacement (AVR). Cardioplexol resulted in immediate cardiac arrest. Intraoperative courses were uneventful. Postoperative markers of myocardial damage, Troponin T and CK-MB levels, were low but steadily increased with longer cross-clamp time. Thirty-day mortality was 3% and all noncardiac. Cardioplexol not only simplifies and speeds up the procedure but also seems to be safe for patients undergoing AVR.

 
  • References

  • 1 Guru V, Omura J, Alghamdi AA, Weisel R, Fremes SE. Is blood superior to crystalloid cardioplegia? A meta-analysis of randomized clinical trials. Circulation 2006; 114 (1) , Suppl) I331-I338
  • 2 Immer FF, Ackermann A, Gygax E , et al. Minimal extracorporeal circulation is a promising technique for coronary artery bypass grafting. Ann Thorac Surg 2007; 84 (5) 1515-1520, discussion 1521
  • 3 Øvrum E, Tangen G, Tølløfsrud S, Øystese R, Ringdal MA, Istad R. Cold blood cardioplegia versus cold crystalloid cardioplegia: a prospective randomized study of 1440 patients undergoing coronary artery bypass grafting. J Thorac Cardiovasc Surg 2004; 128 (6) 860-865
  • 4 Hoelscher B. [INDUCED MAGNESIUM-NOVOCAMIDE HEART ARREST. (LIGHT AND ELECTRON MICROSCOPIC STUDIES)]. Thoraxchir Vask Chir 1965; 13: 95-102
  • 5 Kirsch U, Rodewald G, Kalmár P. Induced ischemic arrest. Clinical experience with cardioplegia in open-heart surgery. J Thorac Cardiovasc Surg 1972; 63 (1) 121-130
  • 6 Kolff WJ, Effler DB, Groves LK, Moraca PP. Elective cardiac arrest with potassium citrate during open-heart operations; report of thirty-seven cases. J Am Med Assoc 1957; 164 (15) 1653-1660
  • 7 Lam CR, Geoghegan T, Lepore A. Induced cardiac arrest for intracardiac surgical procedures; an experimental study. J Thorac Surg 1955; 30 (5) 620-625
  • 8 Melrose DG, Dreyer B, Bentall HH, Baker JB. Elective cardiac arrest. Lancet 1955; 269 (6879) 21-22
  • 9 Braathen B, Tønnessen T. Cold blood cardioplegia reduces the increase in cardiac enzyme levels compared with cold crystalloid cardioplegia in patients undergoing aortic valve replacement for isolated aortic stenosis. J Thorac Cardiovasc Surg 2010; 139 (4) 874-880
  • 10 Lurati Buse GA, Koller MT, Grapow M , et al. 12-month outcome after cardiac surgery: prediction by troponin T in combination with the European system for cardiac operative risk evaluation. Ann Thorac Surg 2009; 88 (6) 1806-1812