Regioselective Palladium(0)-Catalyzed Cross-Coupling Reactions of 5,7-Dichloro-1,6-naphthyridine

Abstract

A variety of mono- and diarylated naphthyridine derivatives were prepared by site-selective Suzuki–Miyaura cross-coupling reactions of 5,7-dichloro-1,6-naphthyridine. The first attack occurs at position 5.

Key Words

catalysis - palladium - Suzuki reaction - naphthyridine - regioselectivity

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