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Synthesis 2012; 44(20): 3109-3128
DOI: 10.1055/s-0032-1316778
DOI: 10.1055/s-0032-1316778
review
1,6-Conjugate Addition of Nucleophiles to α,β,γ,δ-Diunsaturated Systems
Further Information
Publication History
Received: 01 July 2012
Accepted after revision: 07 August 2012
Publication Date:
12 September 2012 (online)
Abstract
Herein, an overview of the most important developments and concepts related to the 1,6-conjugate addition reactions are reviewed.
1 Introduction
2 Transition-Metal-Catalyzed 1,6-Conjugate Additions
2.1 Copper-Mediated Reactions
2.2 Iron-Mediated Reactions
2.3 Rhodium- and Iridium-Mediated Reactions
3 Organocatalyzed 1,6-Conjugate Additions
4 Other Methods
5 Conclusions
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