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Synthesis 2013; 45(2): 246-250
DOI: 10.1055/s-0032-1317895
DOI: 10.1055/s-0032-1317895
paper
Boron Trifluoride as an Efficient Catalyst for the Selective Synthesis of Tricyclic Monoperoxides from β,δ-Triketones and H2O2
Further Information
Publication History
Received: 15 October 2012
Accepted after revision: 22 November 2012
Publication Date:
06 December 2012 (online)
Abstract
Boron trifluoride was found to serve as an efficient catalyst for the reaction of β,δ-triketones with H2O2 producing tricyclic monoperoxides in yields from 48–93%. BF3 acts simultaneously as a catalyst and co-solvent. The synthesis can be scaled up to tens of grams. The resulting peroxides can be easily isolated from the reaction mixture by column chromatography.
Supporting Information
- for this article is available online at http://www.thieme-connect.com/ejournals/toc/synthesis.
- Supporting Information
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