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Synthesis 2013; 45(8): 1051-1059
DOI: 10.1055/s-0032-1318476
DOI: 10.1055/s-0032-1318476
paper
Efficient Transformation of Inactive Nitriles into 5-Substituted 1H-Tetrazoles Using Microwave Irradiation and Their Applications
Further Information
Publication History
Received: 09 January 2013
Accepted after revision: 25 February 2013
Publication Date:
08 March 2013 (online)
Abstract
Efficient transformations of inactive nitriles into 5-substituted 1H-tetrazoles in DMF in a microwave reactor are described. The present method is applied to the synthesis of tetrazolato-bridged dinuclear platinum(II) complex and tetrazole C1-ribonucleoside phosphoramidite.
Supporting Information
- for this article is available online at http://www.thieme-connect.com/ejournals/toc/synthesis. Included are 1H, 13C, 31P and 195Pt NMR spectra for compounds 1t–x, 2h, 6–11, and 3v.
- Supporting Information
-
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For recent reviews on tetrazoles, see: