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Synthesis 2013; 45(12): 1693-1700
DOI: 10.1055/s-0033-1338934
paper
© Georg Thieme Verlag Stuttgart · New York

Synthesis of (+)-Muricatacin and a Formal Synthesis of CMI-977 from l-Malic Acid

Maria González
Departamento de Química Orgánica, Facultade de Química, Universidade de Vigo, 36310 Vigo, Spain   Fax: +34(986)812262   Email: yagamare@uvigo.es   Email: ggomez@uvigo.es
,
Zoila Gándara
Departamento de Química Orgánica, Facultade de Química, Universidade de Vigo, 36310 Vigo, Spain   Fax: +34(986)812262   Email: yagamare@uvigo.es   Email: ggomez@uvigo.es
,
Andrea Martínez
Departamento de Química Orgánica, Facultade de Química, Universidade de Vigo, 36310 Vigo, Spain   Fax: +34(986)812262   Email: yagamare@uvigo.es   Email: ggomez@uvigo.es
,
Generosa Gómez*
Departamento de Química Orgánica, Facultade de Química, Universidade de Vigo, 36310 Vigo, Spain   Fax: +34(986)812262   Email: yagamare@uvigo.es   Email: ggomez@uvigo.es
,
Yagamare Fall*
Departamento de Química Orgánica, Facultade de Química, Universidade de Vigo, 36310 Vigo, Spain   Fax: +34(986)812262   Email: yagamare@uvigo.es   Email: ggomez@uvigo.es
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Further Information

Publication History

Received: 15 March 2013

Accepted after revision: 16 April 2013

Publication Date:
08 May 2013 (online)

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Abstract

A total synthesis of (+)-muricatacin and a formal synthesis of CMI-977 have been achieved using commercially available l-malic acid based on our furan approach to oxacyclic systems, the proven scope of which is thus broadened.

Key words

butenolide - oxygen - natural products - total synthesis - oxidation

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    for this article is available online at http://www.thieme-connect.com/ejournals/toc/synthesis.
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  • References

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