Adipositas und Depressions- und Angstsymptome ­bei prä- und post-menopausalen Frauen: Ein Vergleich verschiedener Adipositasmaße

Zusammenfassung

Die Studie untersucht Unterschiede in der Auftretensrate depressiver und ängstlicher Symptome zwischen über- und normalgewichtigen Frauen vor bzw. nach der Menopause. Bei einer Bevölkerungsstichprobe von 1 416 Teilnehmerinnen des KORA-Survey F3 2004–2005 (35–74 Jahre) wurden Körpermassenindex (BMI), Taillenumfang (WC), Taille-Hüft-Verhältnis (WHR) und Taille-Größe-Verhältnis (WHtR) in einer körperlichen Untersuchung gemessen. Depression und Angst wurden mit der Hospital Anxiety and Depression Scale erhoben. Im Vergleich zu Normalgewicht war Adipositas mit Depression bei prämenopausalen Frauen assoziiert. Dies galt für erhöhte BMI-, WC- und WHtR-Werte (OR=3,7, 4,2 bzw. 2,8), was die Relevanz allgemeiner und abdomineller Adipositas unterstreicht. Der Menopausenstatus könnte ein Moderator für die Assoziation von Adipositas und Depression darstellen, was angesichts der Interaktion dieser Risikofaktoren auch präventiv bei der Entstehung kardiovaskulärer Outcomes wie der koronaren Herzkrankheit bedeutsam sein könnte.

Abstract

This study examines differences in the rates of depression and anxiety symptoms in overweight vs. normal weight women before and after the menopause. In a population sample of 1 416 participants of the KORA-Survey F3 2004–2005 (age 35–74 years), body mass index (BMI), waist circumference (WC), waist-to-hip-ratio (WHR) und waist-to-height-ratio (WHtR) were measured via physical examination. Depression and anxiety were assessed with the Hospital Anxiety and Depression Scale. Compared with normal weight, obesity was associated with depression in premenopausal women. This held for elevated BMI-, WC- and WHtR-scores (OR=3.7, 4.2, and 2.8), underlining the relevance of both general and abdominal obesity. Menopausal status may be a moderator for the association of obesity and depression, which – given the interaction between these 2 risk factors – may be of preven­tive importance in regard to the development of cardiovascular outcomes such as coronary heart disease.

Schlüsselwörter

Adipositas - Depression - Angst - Frauen - Menopause

Keywords

obesity - depression - anxiety - women - menopause

^* Gleichwertiger Beitrag/geteilte Erstautorenschaft.

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