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Am J Perinatol 2014; 31(S 01): S19-S24
DOI: 10.1055/s-0034-1378143
Review Article
Thieme Medical Publishers 333 Seventh Avenue, New York, NY 10001, USA.

Fetoscopic Laser Therapy for Twin–Twin Transfusion Syndrome: Beyond Current Gestational Age Limits

David Baud
1   Fetal Medicine Unit, Mount Sinai Hospital, University of Toronto, Toronto, Ontario, Canada
2   Swiss Laser Group, University Hospitals of Lausanne and Inselspital-Bern, Switzerland
,
Rory Windrim
1   Fetal Medicine Unit, Mount Sinai Hospital, University of Toronto, Toronto, Ontario, Canada
,
Johannes Keunen
1   Fetal Medicine Unit, Mount Sinai Hospital, University of Toronto, Toronto, Ontario, Canada
,
Greg Ryan
1   Fetal Medicine Unit, Mount Sinai Hospital, University of Toronto, Toronto, Ontario, Canada
› Author Affiliations
Further Information

Publication History

09 January 2014

18 April 2014

Publication Date:
24 June 2014 (online)

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Abstract

Both “early” (< 16 weeks' gestation) and “late” (> 26 weeks' gestation) presentations of twin–twin transfusion syndrome (TTTS) are rare and challenging complications of monochorionic/diamniotic twin pregnancies. Growing evidence suggests that fetoscopic laser therapy for both “early” and “late” TTTS is feasible, safe, and yields similar outcomes to cases treated between 16 and 26 weeks' gestation. We suggest reevaluation of conventional gestational age guidelines for laser therapy for TTTS.

Keywords

laser therapy - fetoscopy - monochorionic twins - neonatal mortality - twin–twin transfusion syndrome

Presentation Information

This work was presented at (1) TTTS Workshop 2013, Houston, Texas, June 2013 (oral); (2) 11th World Congress in Fetal Medicine, June 24, 2012, to June 28, 2012, Kos, Greece (oral); (3) 22nd International Society of Ultrasound in Obstetrics and Gynecology (ISUOG), September 9, 2012, to September 12, 2012, Copenhagen, Denmark (poster).


Article Condensation


Perinatal outcome following fetoscopic laser therapy for severe TTTS outside the “conventional” 16 to 26 week' GA range is associated with a comparable perinatal outcome.


 

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