Iodofluorination of Alkenes Using IF₅–Pyridine–HF

Abstract

Iodofluorination of alkenes was performed by using IF₅–pyridine–HF and a reductant such as potassium iodide or tin powder. The addition of IF to the double bond proceeded with stereo- and regioselectivity. In the reaction with internal alkenes, the trans-addition product was obtained selectively. With terminal alkenes, the addition took place regioselectively to give 1-iodo-2-fluoroalkanes.

Key words

fluorine - addition - stereoselective synthesis - halogenation - alkenes

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