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J Reconstr Microsurg 2016; 32(01): 034-041
DOI: 10.1055/s-0035-1554934
Invited Review
Thieme Medical Publishers 333 Seventh Avenue, New York, NY 10001, USA.

Microsurgical Lymphatic Vessel Transplantation

Ruediger G. H. Baumeister
1   Consultant in Lymphology, Chirurgische Klinik Muenchen Bogenhausen, München, Germany
2   Division of Hand Surgery, Plastic- and Aesthetic Surgery, AUHP Klinik, Ludwig Maximilians University of Munich, Muenchen, Germany
,
Weiss Mayo
3   Department of Nuclear Medicine, Ludwig Maximilians University of Munich, München, Germany
,
Mike Notohamiprodjo
4   Institute for Cinical Radiology, Ludwig Maximilians University of Munich, München, Germany
,
Jens Wallmichrath
2   Division of Hand Surgery, Plastic- and Aesthetic Surgery, AUHP Klinik, Ludwig Maximilians University of Munich, Muenchen, Germany
,
Stephanie Springer
2   Division of Hand Surgery, Plastic- and Aesthetic Surgery, AUHP Klinik, Ludwig Maximilians University of Munich, Muenchen, Germany
,
Andreas Frick
2   Division of Hand Surgery, Plastic- and Aesthetic Surgery, AUHP Klinik, Ludwig Maximilians University of Munich, Muenchen, Germany
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Publikationsverlauf

22. Februar 2015

28. März 2015

Publikationsdatum:
10. Juli 2015 (online)

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Abstract

Background Lymphedema often arises after a regional interruption during cancer treatment, for example after lymph node resection the axilla or the groin. Lymphatic vessels as vascular grafts may overcome these lymphatic gaps.

Method Experiments in rats and dogs were performed for developing this method. Volume measurements, lymphoscintigraphies, proof of patency by MRI and radiology as well as quality of life studies were performed in patients.

Results Long-term follow-up studies revealed significantly reduced volumes, significant improvement of lymphatic outflow shown by lymphoscintigraphy, long-term patency of the grafts for more than 10 years, and improved quality of life after surgery compared with the situation with conservative treatment before surgery.

Conclusion Vascular grafts using the patients own lymphatic vessels are able to successfully reconstruct a locally interrupted lymphatic pathway.

Keywords

lymphedema - lymphatic vessel - vascular graft - microsurgery
 

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