Journal of Reconstructive Microsurgery, Table of Contents J Reconstr Microsurg 2015; 31(07): 544-546DOI: 10.1055/s-0035-1555011 Letter to the Editor: Short Report Thieme Medical Publishers 333 Seventh Avenue, New York, NY 10001, USA.Eptifibatide Salvage of Arterial Anastomotic Thrombosis in Lower Extremity Free Flap Reconstruction: A Case Report Authors Author Affiliations Tessa Drijkoningen 1 Division of Plastic and Reconstructive Surgery, Massachusetts General Hospital, Harvard Medical School, Boston, Massachusetts Vincent van Weel 2 Department of Surgery, Meander Medical Center, Amersfoort, The Netherlands Kyle R. Eberlin 1 Division of Plastic and Reconstructive Surgery, Massachusetts General Hospital, Harvard Medical School, Boston, Massachusetts Curtis L. Cetrulo Jr. 1 Division of Plastic and Reconstructive Surgery, Massachusetts General Hospital, Harvard Medical School, Boston, Massachusetts Recommend Article Abstract Buy Article(opens in new window) Full Text References References 1 Choudry U, Moran S, Karacor Z. Soft-tissue coverage and outcome of gustilo grade IIIB midshaft tibia fractures: a 15-year experience. Plast Reconstr Surg 2008; 122 (2) 479-485 2 Yazar S, Lin CH, Lin YT, Ulusal AE, Wei FC. Outcome comparison between free muscle and free fasciocutaneous flaps for reconstruction of distal third and ankle traumatic open tibial fractures. Plast Reconstr Surg 2006; 117 (7) 2468-2475 , discussion 2476–2477 3 Bui DT, Cordeiro PG, Hu QY, Disa JJ, Pusic A, Mehrara BJ. Free flap reexploration: indications, treatment, and outcomes in 1193 free flaps. Plast Reconstr Surg 2007; 119 (7) 2092-2100 4 Lee DS, Jung SI, Kim DW, Dhong ES. Anterograde intra-arterial urokinase injection for salvaging fibular free flap. Arch Plast Surg 2013; 40 (3) 251-255 5 Askari M, Fisher C, Weniger FG, Bidic S, Lee WP. Anticoagulation therapy in microsurgery: a review. J Hand Surg Am 2006; 31 (5) 836-846 6 Cooley BC, Gould JS. Experimental models for evaluating antithrombotic therapies in replantation microsurgery. Microsurgery 1987; 8 (4) 230-233 7 Basile AP, Fiala TG, Yaremchuk MJ, May Jr JW. The antithrombotic effects of ticlopidine and aspirin in a microvascular thrombogenic model. Plast Reconstr Surg 1995; 95 (7) 1258-1264 8 Khouri RK, Sherman R, Buncke Jr HJ , et al. A phase II trial of intraluminal irrigation with recombinant human tissue factor pathway inhibitor to prevent thrombosis in free flap surgery. Plast Reconstr Surg 2001; 107 (2) 408-415 , discussion 416–418 9 ESPRIT Investigators. Enhanced Suppression of the Platelet IIb/IIIa Receptor with Integrilin Therapy. Novel dosing regimen of eptifibatide in planned coronary stent implantation (ESPRIT): a randomised, placebo-controlled trial. Lancet 2000; 356 (9247) 2037-2044 10 Blankenship JC, Sigmon KN, Pieper KS, O'Shea C, Tardiff BE, Tcheng JE ; IMPACT-II Investigators. Effect of eptifibatide on angiographic complications during percutaneous coronary intervention in the IMPACT—(Integrilin to Minimize Platelet Aggregation and Coronary Thrombosis) II Trial. Am J Cardiol 2001; 88 (9) 969-973