Synlett 2016; 27(09): 1387-1390
DOI: 10.1055/s-0035-1561575
letter
© Georg Thieme Verlag Stuttgart · New York

Catalyst-Free Synthesis of 2-Arylbenzothiazoles in an Air/DMSO Oxidant System

Renhe Hu
a   College of Biotechnology and Pharmaceutical Engineering, Nanjing Tech University, Nanjing 211816, P. R. of China   Email: hanshiqing@njtech.edu.cn
,
Xiaotong Li
a   College of Biotechnology and Pharmaceutical Engineering, Nanjing Tech University, Nanjing 211816, P. R. of China   Email: hanshiqing@njtech.edu.cn
,
Yao Tong
a   College of Biotechnology and Pharmaceutical Engineering, Nanjing Tech University, Nanjing 211816, P. R. of China   Email: hanshiqing@njtech.edu.cn
,
Dazhuang Miao
a   College of Biotechnology and Pharmaceutical Engineering, Nanjing Tech University, Nanjing 211816, P. R. of China   Email: hanshiqing@njtech.edu.cn
,
Qiang Pan
a   College of Biotechnology and Pharmaceutical Engineering, Nanjing Tech University, Nanjing 211816, P. R. of China   Email: hanshiqing@njtech.edu.cn
,
Zengqiang Jiang
a   College of Biotechnology and Pharmaceutical Engineering, Nanjing Tech University, Nanjing 211816, P. R. of China   Email: hanshiqing@njtech.edu.cn
,
Haifeng Gan
a   College of Biotechnology and Pharmaceutical Engineering, Nanjing Tech University, Nanjing 211816, P. R. of China   Email: hanshiqing@njtech.edu.cn
,
Shiqing Han*
a   College of Biotechnology and Pharmaceutical Engineering, Nanjing Tech University, Nanjing 211816, P. R. of China   Email: hanshiqing@njtech.edu.cn
b   Key Laboratory of Synthetic Chemistry of Natural Substances, Shanghai Institute of Organic Chemistry, CAS, 345 Lingling Road, Shanghai 200032, P. R. of China
› Author Affiliations
Further Information

Publication History

Received: 04 November 2015

Accepted after revision: 23 January 2016

Publication Date:
25 February 2016 (online)


Abstract

A straightforward strategy for the synthesis of 2-arylbenzothiazoles from 2-aminothiophenol and aryl aldehydes in air/DMSO oxidant system has been developed. This reaction is operationally simple, proceeds without catalysts, tolerates a wide range of functionalities, and provides desired products in good to excellent yields.

Supporting Information