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Synthesis 2017; 49(21): 4893-4898
DOI: 10.1055/s-0036-1588496
DOI: 10.1055/s-0036-1588496
paper
Aluminum Chloride Promoted Hantzsch Reaction of N-Tosylhydrazones
Authors
Further Information
Publication History
Received: 19 April 2017
Accepted after revision: 09 June 2017
Publication Date:
25 July 2017 (online)
Abstract
An aluminum chloride promoted Hantzsch reaction of N-tosylhydrazones has been developed. The reaction is general for a wide range of N-tosylhydrazones, and a series of 1,4-dihydropyridines (1,4-DHPs) were prepared in moderate to excellent yields.
Key words
synthetic method - aluminum chloride - Hantzsch reaction - N-tosylhydrazones - 1,4-dihydropyridinesSupporting Information
- Supporting information for this article is available online at https://doi.org/10.1055/s-0036-1588496.
- Supporting Information (PDF) (opens in new window)
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References
- 1 Cominsa DL. Higuchib K. Young DW. Adv. Heterocycl. Chem. 2013; 110: 175
- 2 Wan J.-P. Liu Y. RSC Adv. 2012; 2: 9763
- 3 Biggs-Houck JE. Younai A. Shaw JT. Curr. Opin. Chem. Biol. 2010; 14: 371
- 4 Saini A. Rumar S. Sandhu JS. J. Sci. Ind. Res. 2008; 67: 95
- 5 Eynde JJ. V. Mayence A. Molecules 2003; 8: 381
- 6 Khedkar SA. Auti PB. Mini Rev. Med. Chem. 2014; 14: 282
- 7 Vijesh AM. Isloor AM. Peethambar SK. Shivananda KN. Arulmoli T. Isloor NA. Eur. J. Med. Chem. 2011; 46: 5591
- 8 Nguyen QP. B. Kim JN. Kim TH. Tetrahedron 2012; 68: 6513
- 9 Zheng C. You S.-L. Chem. Soc. Rev. 2012; 41: 2498
- 10 Ouellet SG. Walji AM. MacMillan DW. C. Acc. Chem. Res. 2007; 40: 1327
- 11 Yoo JS. Laughlin TJ. Krob JJ. Mohan RS. Tetrahedron Lett. 2015; 56: 4060
- 12 Li J. He P. Yu C. Tetrahedron 2012; 68: 4138
- 13 Evans CG. Gestwicki JE. Org. Lett. 2009; 11: 2957
- 14 Kikuchi S. Iwai M. Murayama H. Fukuzawa S.-I. Tetrahedron Lett. 2008; 49: 114
- 15 Xiao Q. Zhang Y. Wang J. Acc. Chem. Res. 2013; 46: 236
- 16 Zhang Y. Wang J. Top. Curr. Chem. 2012; 327: 239
- 17 Shao Z. Zhang H. Chem. Soc. Rev. 2012; 41: 560
- 18 Huang Y. Li X. Yu Y. Zhu C. Wu W. Jiang H. J. Org. Chem. 2016; 81: 5014
- 19 Tang M. Wang Y. Wang H. Kong Y. Synthesis 2016; 48: 3065
- 20 Kong Y. Tang M. Wang Y. Org. Lett. 2014; 16: 576
- 21 Tang M. Zhang F.-M. Tetrahedron 2013; 69: 1427
- 22 Tang M. Zhang W. Kong Y. Org. Biomol. Chem. 2013; 11: 6250
- 23 Tang M. Kong Y. Chu B. Feng D. Adv. Synth. Catal. 2016; 358: 926
- 24 Zhao Y.-H. Li Y. Luo M. Tang Z. Deng K. Synlett 2016; 27: 2597
- 25 Kong Y. Zhang W. Tang M. Wang H. Tetrahedron 2013; 69: 7487
- 26 Kumar A. Maurya RA. Sharma S. Bioorg. Med. Chem. Lett. 2009; 19: 4432