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Synthesis 2018; 50(03): 575-582
DOI: 10.1055/s-0036-1591505
DOI: 10.1055/s-0036-1591505
paper
Synthesis of 4-Aryl-3-arylthio-3,4-dihydroquinolin-2(1H)-ones via Cyclization of N-Arylcinnamamides with N-Thiosuccinimides
This work was financially supported by the National Natural Science Foundation of China (Grant No. 21262017 and No. 21366023), Jiangxi Provincial Department of Science and Technology (Grant No. 20132BAB203035), and Jiangxi Provincial Department of Education (Grant No. GJJ13531).Weitere Informationen
Publikationsverlauf
Received: 04. August 2017
Accepted after revision: 03. Oktober 2017
Publikationsdatum:
19. Oktober 2017 (online)
Abstract
cis-4-Aryl-3-arylthio-3,4-dihydroquinolin-2(1H)-ones were synthesized via electrophilic sulfenylation and cyclization of N-arylcinnamamides with N-arylthiosuccinimides in the presence of boron trifluoride etherate. The cis-products were obtained with high stereoselectivity.
Key words
cylization - electrophilic reaction - sulfenylation - N-arylcinnamamides - N-arylthiosuccinimidesSupporting Information
- Supporting information for this article is available online at https://doi.org/10.1055/s-0036-1591505.
- Supporting Information
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