Am J Perinatol 2017; 34(05): 465-470
DOI: 10.1055/s-0036-1593348
Original Article
Thieme Medical Publishers 333 Seventh Avenue, New York, NY 10001, USA.

Short-Term Perinatal Outcome among Term Infants with Prenatal Diagnosis of Large Abdominal Circumference

Guy Steinberg-Barkon*
1   Sackler Faculty of Medicine, Department of Pediatrics, Tel Aviv University, Tel Aviv, Israel
,
Leah Leibovitch*
1   Sackler Faculty of Medicine, Department of Pediatrics, Tel Aviv University, Tel Aviv, Israel
2   Department of Neonatology, Edmond and Lily Safra Children's Hospital, Sheba Medical Center, Tel HaShomer, Israel
,
Irit Schushan-Eisen
1   Sackler Faculty of Medicine, Department of Pediatrics, Tel Aviv University, Tel Aviv, Israel
2   Department of Neonatology, Edmond and Lily Safra Children's Hospital, Sheba Medical Center, Tel HaShomer, Israel
,
Liat Gindes
3   Department of Obstetrics, Sheba Medical Center, Tel HaShomer, Israel
,
Tzipora Strauss
1   Sackler Faculty of Medicine, Department of Pediatrics, Tel Aviv University, Tel Aviv, Israel
2   Department of Neonatology, Edmond and Lily Safra Children's Hospital, Sheba Medical Center, Tel HaShomer, Israel
,
Ayala Maayan-Metzger
1   Sackler Faculty of Medicine, Department of Pediatrics, Tel Aviv University, Tel Aviv, Israel
2   Department of Neonatology, Edmond and Lily Safra Children's Hospital, Sheba Medical Center, Tel HaShomer, Israel
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Publikationsverlauf

27. Mai 2016

15. August 2016

Publikationsdatum:
21. September 2016 (online)

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Abstract

Background Measuring fetal abdominal circumference (AC) prenatally is an effective tool for predicting neonatal weight and macrosomia. Data are lacking regarding the outcome of newborn infants with prenatal diagnosis of large AC.

Aim The aim of this study was to evaluate early short-term neonatal outcome among term singleton newborn infants with prenatal diagnosis of large AC.

Methods Retrospective data were collected on 501 term infants with prenatal diagnosis of large AC (≥ 360 mm) and on matched controls, including information on maternal condition and on infant perinatal complications.

Results In compare with controls, the study group had higher incidence of macrosomia (188 [37.5%] vs. 18 [3.6%], p < 0.001), hypoglycemia (48 (9.6%) vs. 25 [5%], p = 0.007), and significant morbidity (49 [9.8%] vs. 28 [5.6%], p = 0.017) but without increased incidence of congenital malformations or other perinatal complications. Only among the macrosomic, study subgroup and their controls differences were recorded including hypoglycemia (17.6 vs. 4.8%, p < 0.001), need for oral glucose (11.2 vs. 2.7%, p = 0.002), significant morbidity (10.1 vs. 3.7%, p = 0.024), and hospitalization in special care unit (11.7 vs. 4.3%, p = 0.012).

Conclusion Prelabor diagnosis of large AC mostly reflects the infant's high birth weight and macrosomia with the associated perinatal complications. Large AC by itself was not predictive of any congenital malformations or perinatal and postnatal complications.

Note

This work was performed in partial fulfillment of the M.D. thesis requirements of the Sackler Faculty of Medicine, Tel Aviv University. The authors disclosed all source of financial support for the study.


* Both authors contributed equally to the article as first authors from different disciplines.