Semin intervent Radiol 2017; 34(02): 092-100
DOI: 10.1055/s-0037-1602591
Review Article
Thieme Medical Publishers 333 Seventh Avenue, New York, NY 10001, USA.

Decision Making: Intra-arterial Therapies for Cholangiocarcinoma—TACE and TARE

Brian M. Currie
1   Department of Radiology, Hospital of the University of Pennsylvania, Philadelphia, Pennsylvania
,
Michael C. Soulen
1   Department of Radiology, Hospital of the University of Pennsylvania, Philadelphia, Pennsylvania
› Author Affiliations
Further Information

Publication History

Publication Date:
01 June 2017 (online)

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Abstract

The incidence of intrahepatic cholangiocarcinoma (ICC) has been increasing in recent years and now represents the second most common primary hepatic cancer in the United States. The prognosis is dismal without surgical resection. In patients ineligible to receive curative treatments, locoregional therapies represent a diverse array of techniques that can stabilize or reverse tumor progression to improve overall survival and reduce tumor-related symptoms. Transarterial chemoembolization (TACE) and transarterial radioembolization (TARE) have been demonstrated to be efficacious methods for this patient population. Deciding between these two options is challenging. This article reviews the differences in patient selection, preprocedural evaluation, financial considerations and availability, quality of life, and rates of complications and overall survival.