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Thromb Haemost 1998; 79(05): 1055-1056
DOI: 10.1055/s-0037-1615120
DOI: 10.1055/s-0037-1615120
Letters to the Editor
Detection of the 20210 A/G Variation in the Prothrombin Gene by Denaturing Gradient Gel Electrophoresis (DGGE)
Further Information
Publication History
Received
08 December 1997
Accepted after revision
29 January 1998
Publication Date:
07 December 2017 (online)
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References
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- 2 Poort SR, Bertina RM, Vos HL. Rapid detection of the prothrombin 20210 A variation by allele specific PCR. Thromb Haemost 1997; 78: 1157-8.
- 3 Myers RM, Maniatis T, Lerman LS. Detection and localization of single base change by denaturing gradient gel electrophoresis. Methods Enzymol 1987; 155: 501-27.
- 4 Degen SJ, Davie EW. Nucleotide sequence of the gene for human prothrombin. Biochem 1987; 26: 6165-77.
- 5 Bancroft JD, Schaefer LA, Degen SJ. Characterization of the Alu-rich 5’-flanking region of the human prothrombin-encoding gene: identification of a positive cis-acting element that regulates liver-specific expression. Gene 1990; 95: 253-60.
- 6 Sheffield VC, Cox DR, Lerman LS, Myers RM. Attachment of a 40-base-pair G+C-rich sequence (GC clamp) to genomic DNA fragments by the polymerase chain reaction results in improved detection of single-base changes. Proc Natl Acad Sci USA 1989; 86: 232-6.