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Thromb Haemost 1999; 82(02): 576-584
DOI: 10.1055/s-0037-1615883
Research Article
Schattauer GmbH

Structure and Function of von Willebrand Factor

Zaverio M. Ruggeri
1   Roon Research Center for Arteriosclerosis and Thrombosis, Division of Experimental Hemostasis and Thrombosis, Department of Molecular and Experimental Medicine, Department of Vascular Biology, The Scripps Research Institute, La Jolla, CA, USA
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Publication Date:
09 December 2017 (online)

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Introduction

The reader will find here a concise summary of established notions on the structure and function of von Willebrand factor (vWF), followed by a brief discussion of selected recent advances that illustrate how this molecule supports platelet function in hemostasis and thrombosis. A comprehensive review of the topic is beyond the scope of this chapter and may be found elsewhere.1-3

 

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