Introduction
The antiphospholipid syndrome (APS) is an autoimmune condition in which a group of
autoantibodies are thought to play a direct role in the pathogenesis of thrombosis,
fetal loss, and other clinical manifestations. This review will focus on the nature
of these autoantibodies, the antigens they recognize, and mechanisms that may contribute
to autoimmunity and the production of autoantibodies in patients with APS.