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Vet Comp Orthop Traumatol 2005; 18(03): 157-168
DOI: 10.1055/s-0038-1632947
Original Research
Schattauer GmbH

Evaluation of healing in feline femoral defects filled with cancellous autograft, cancellous allograft or Bioglass

H. C. Dorea
1   Departments of Clinical Sciences
,
R. M. McLaughlin
1   Departments of Clinical Sciences
,
H. D. Cantwell
1   Departments of Clinical Sciences
,
R. Read
,
L. Armbrust
3   Department of Clinical Sciences, College of Veterinary Medicine, Kansas State University, Manhattan, Kansas, USA
,
R. Pool
4   Department of Veterinary Pathology, College of Veterinary Medicine, Texas A&M University, College Station Texas, USA
,
J. K. Roush
3   Department of Clinical Sciences, College of Veterinary Medicine, Kansas State University, Manhattan, Kansas, USA
,
C. Boyle
5   Basic Sciences, College of Veterinary Medicine, Mississippi State University, Mississippi, USA
› Author Affiliations
Further Information

Publication History

Received 07 June 2004

Accepted 14 January 2005

Publication Date:
22 February 2018 (online)

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Summary

Cancellous bone grafting is a widely accepted technique in human and veterinary orthopaedic surgery. However, the use of autogenous bone graft is limited by the additional surgical time required to harvest the graft, the morbidity associated with the donor site, and the limited availability of cancellous bone, especially in feline patients. Various allografts and bone graft substitutes are available commercially but have not been fully evaluated for efficacy in the cat. The purpose of this study was to compare the incorporation of autogenous and allogenous cancellous bone graft and Bioglass®, a synthetic bone graft substitute, in femoral defects in cats. Four (4.0 mm diameter) defects were created in the lateral diaphyseal cortex of the left femur with an orthopaedic drill. In each femur, one of the cortical defects was filled with autogenous cancellous graft (harvested from the tibia), one was filled with allogenic cancellous graft, and one was filled with Bioglass. The fourth defect remained unfilled. Graft incorporation within the femoral defects was evaluated by radiographic evaluation every two weeks. Six weeks after the grafting procedure, the cats were euthanatized and high detailed radiography, dual energy X-ray absorptiometry (DEXA), histopathology and histomorphometry of the defects were performed. Satisfactory bone healing was observed within all of the defects.

Keywords

Bone grafts - cancellous autograft - cancellous allograft - Bioglass® - feline
 

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