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Thromb Haemost 1996; 75(04): 560-561
DOI: 10.1055/s-0038-1650321
Original Article
Schattauer GmbH Stuttgart

Platelet Density and Size in Inflammatory Bowel Disease

P Järemo
The Department of Clinical Chemistry and the Unit of Gastroenterology, Department of Medicine, Örebro Medical Center Hospital, Örebro, Sweden
,
H Sandberg-Gertzen
The Department of Clinical Chemistry and the Unit of Gastroenterology, Department of Medicine, Örebro Medical Center Hospital, Örebro, Sweden
› Author Affiliations
Further Information

Publication History

Received 01 August 1995

Accepted after resubmission 15 December 1995

Publication Date:
10 July 2018 (online)

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Summary

Objective: The present study investigates platelet density and mean platelet volume (MPV) in active inflammatory bowel disease (IBD).

Experimental protocol: 27 patients with IBD (18 ulcerative colitis and 9 Crohn’s disease) were compared to 12 healthy volunteers. 18 subjects had active disease. Platelet counts and mean platelet volume (MPV) were determined. Thereafter, platelets were separated according to density on a linear preformed Percoll gradient. A computerized device was employed for scanning transmission variations and thus the platelet distribution in the gradient and the platelet peak were identified.

 

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