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Thromb Haemost 1981; 46(04): 717-721
DOI: 10.1055/s-0038-1653460
Original Article
Schattauer GmbH Stuttgart

Glanzmann’s Thrombasthenia

A Review and Report of 42 Cases from South India
U Khanduri
The Dept. of Clinical Pathology and Blood Bank, Vellore Tamil Nadu, India
,
R Pulimood
The Dept. of Clinical Pathology and Blood Bank, Vellore Tamil Nadu, India
,
A Sudarasanam
The Dept. of Clinical Pathology and Blood Bank, Vellore Tamil Nadu, India
,
R H Carman
The Dept. of Clinical Pathology and Blood Bank, Vellore Tamil Nadu, India
,
M Jadhav
*   The Dept. of Child Health Christian Medical College Hospital, Vellore Tamil Nadu, India
,
S Pereira
*   The Dept. of Child Health Christian Medical College Hospital, Vellore Tamil Nadu, India
› Author Affiliations
Further Information

Publication History

Received 10 March 1981

Accepted 01 October 1981

Publication Date:
05 July 2018 (online)

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Summary

In the 14 year period from June, 1966 to June, 1980, 42 cases of Glanzmann’s thrombasthenia have been diagnosed, all fulfilling the criteria of prolonged bleeding time, with normal venous platelet count, defective clot retraction and decreased platelet aggregation, associated with a lifelong bleeding tendency. Few cases have been reported from India though it is the fourth most common congenital bleeding disorder among the patients seen at the Christian Medical College Hospital, Vellore. The large number of such cases found in South India as compared with reports from other parts of the world may be due to the high degree of consanguinity which is part of the accepted culture in this area. Reliable diagnosis of this condition is possible with fairly simple laboratory procedures.

Keywords

Glanzmann’s thrombasthenia - Consanguinity
 

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