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Thromb Haemost 1985; 53(01): 005-007
DOI: 10.1055/s-0038-1661225
Original Article
Schattauer GmbH Stuttgart

High Levels of Plasma Protein C in Nephrotic Syndrome

I Pabinger-Fasching
The First Department of Internal Medicine (Head: Prof. Dr. Dr. h. c. E. Deutsch), Division of Hematology and Blood Coagulation, University of Vienna, Austria
,
K Lechner
The First Department of Internal Medicine (Head: Prof. Dr. Dr. h. c. E. Deutsch), Division of Hematology and Blood Coagulation, University of Vienna, Austria
,
H Niessner
The First Department of Internal Medicine (Head: Prof. Dr. Dr. h. c. E. Deutsch), Division of Hematology and Blood Coagulation, University of Vienna, Austria
,
P Schmidt
The First Department of Internal Medicine (Head: Prof. Dr. Dr. h. c. E. Deutsch), Division of Hematology and Blood Coagulation, University of Vienna, Austria
,
E Balzar
1   The Department of Pediatrics1 (Head: Prof. Dr. E. Zweymüller), University of Vienna, Austria
,
Ch Mannhalter
The First Department of Internal Medicine (Head: Prof. Dr. Dr. h. c. E. Deutsch), Division of Hematology and Blood Coagulation, University of Vienna, Austria
› Author Affiliations
Further Information

Publication History

Received 15 June 1984

Accepted 24 September 1984

Publication Date:
18 July 2018 (online)

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Summary

In patients with severe nephrotic syndrome determinations of plasma protein C : Ag levels (8 patients: 5 adults, 3 children) and protein C activity (3 out of 8 patients) revealed significantly elevated plasma protein C concentrations. Furthermore we observed a significant inverse correlation of protein C : Ag to AT III : Ag levels. No protein C : Ag could be detected in the urine of two patients studied. We conclude from our data, that changes of plasma protein C do not contribute to the high thrombotic tendency in nephrotic syndrome.

Key words

Protein C - Nephrotic syndrome - AT III - Coagulation inhibitors in patients with nephrotic syndrome
 

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