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Synthesis 2019; 51(22): 4271-4278
DOI: 10.1055/s-0039-1690612
DOI: 10.1055/s-0039-1690612
paper
Ruthenium-Catalyzed [2+2+2] Bis-Homo-Diels–Alder Cycloadditions of 1,5-Cyclooctadiene with Alkynyl Phosphonates
This work was supported by the Natural Sciences and Engineering Council of Canada (NSERC).Further Information
Publication History
Received: 16 July 2019
Accepted after revision: 31 July 2019
Publication Date:
21 August 2019 (online)
Abstract
The ruthenium-catalyzed [2+2+2] bis-homo-Diels–Alder cycloaddition between 1,5-cyclooctadiene and alkynyl phosphonates was investigated. Various alkynyl phosphonate moieties were found to be compatible with the cycloaddition to give the tricyclo[4.2.2.02,5]dec-7-ene tricyclic compounds in yields of 46–97%.
Key words
1,5-cyclooctadiene - bis-homo-Diels–Alder reaction - cycloaddition - ruthenium-catalyzed - alkynyl phosphonateSupporting Information
- Supporting information for this article is available online at https://doi.org/10.1055/s-0039-1690612.
- Supporting Information
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