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CC BY-NC-ND 4.0 · Semin Thromb Hemost 2019; 45(05): 433-448
DOI: 10.1055/s-0039-1692700
Review Article
Thieme Medical Publishers 333 Seventh Avenue, New York, NY 10001, USA.

Preanalytical Variables in Coagulation Testing: Setting the Stage for Accurate Results

Robert C. Gosselin
1   Hemostasis and Thrombosis Center, Davis Health System, University of California, Sacramento, California
,
Richard A. Marlar
2   Department of Pathology, University of New Mexico Health Sciences Center, Albuquerque, New Mexico
› Author Affiliations
Further Information

Publication History

Publication Date:
10 July 2019 (online)

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Abstract

Many preanalytical variables may affect the results of routine coagulation assays. While advances in laboratory instrumentation have partially addressed the laboratory's ability to recognize some of these variables, there remains an increased reliance on laboratory personnel to recognize the three potential areas where coagulation testing preanalytical issues may arise: (1) specimen collection (including patient selection), (2) specimen transportation and stability, and (3) specimen processing and storage. The purpose of this article is to identify the preanalytical variables associated with coagulation-related testing and provide laboratory practice recommendations in an effort to improve the quality of coagulation testing and accuracy of result reporting.

Keywords

coagulation testing - preanalytical variables - recommendations - specimens
 

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