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Synthesis 2020; 52(19): 2821-2827
DOI: 10.1055/s-0040-1707179
DOI: 10.1055/s-0040-1707179
feature
Annulations with Butenolides and Phthalides: New Entries to Isocoumarins, 3,4-Dihydroisocoumarins, and Benzofurans
We thank the National Science Foundation (NSF) EAGER funding (Award #1842604) for partial support of this research, and Iowa State University, Department of Chemistry.Further Information
Publication History
Received: 28 April 2020
Accepted after revision: 03 June 2020
Publication Date:
16 July 2020 (online)
Abstract
The reactions of the anions of butenolides and substituted phthalides with sorbate esters and mono-epoxy sorbate esters furnish isocoumarins, 3,4-dihydroisocoumarins, and benzofurans. The yields range from 41% to 71%.
Key words
butenolides - phthalides - sorbate esters - epoxy sorbates - polycyclic ring - isocoumarins - benzofurans - cyclic annulationSupporting Information
- Supporting information for this article is available online at https://doi.org/10.1055/s-0040-1707179.
- Supporting Information
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