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CC BY-NC-ND 4.0 · Journal of Clinical Interventional Radiology ISVIR 2022; 06(03): 163-169
DOI: 10.1055/s-0041-1740570
Original Article

Percutaneous Cryoablation of Renal Tumors: Initial Indian Experience

Authors

  • Ujjwal Gorsi

    1   Department of Radiodiagnosis, Postgraduate Institute of Medical Education and Research (PGIMER), Chandigarh, India

  • Rishabh Jain

    1   Department of Radiodiagnosis, Postgraduate Institute of Medical Education and Research (PGIMER), Chandigarh, India

  • Akash Bansal

    1   Department of Radiodiagnosis, Postgraduate Institute of Medical Education and Research (PGIMER), Chandigarh, India

  • Naveen Kalra

    1   Department of Radiodiagnosis, Postgraduate Institute of Medical Education and Research (PGIMER), Chandigarh, India

  • Mandeep Kang

    1   Department of Radiodiagnosis, Postgraduate Institute of Medical Education and Research (PGIMER), Chandigarh, India

  • Sreedhara B. Chaluvashetty

    1   Department of Radiodiagnosis, Postgraduate Institute of Medical Education and Research (PGIMER), Chandigarh, India

  • Ravimohan Suryanarayan Mavuduru

    2   Department of Urology, Postgraduate Institute of Medical Education and Research (PGIMER), Chandigarh, India

  • Santosh Kumar

    2   Department of Urology, Postgraduate Institute of Medical Education and Research (PGIMER), Chandigarh, India

  • Shrawan K. Singh

    2   Department of Urology, Postgraduate Institute of Medical Education and Research (PGIMER), Chandigarh, India

  • Manavjit Singh Sandhu

    1   Department of Radiodiagnosis, Postgraduate Institute of Medical Education and Research (PGIMER), Chandigarh, India
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Abstract

Purpose The purpose of this study was to report short-term outcomes of cryoablation of early-stage renal tumors (T1a and T1b) at a tertiary hospital in India.

Methods This was a retrospective study of consecutive patients who underwent cryoablation for renal cell carcinoma (RCC) from November 2018 to June 2020. Cryoablation was performed under combined ultrasound and computed tomography guidance using a helium-argon cryoablation system. Tumor number, size, location, nephrometry score, relationship of the tumor with pelvicalyceal system, and adjacent organs were tabulated, and technical and clinical success evaluated. Early and late recurrence and complications were also assessed.

Results Eleven patients (median age: 62 years) with 11 tumors underwent cryoablation. The mean tumor size was 2.58 cm (range: 1.62–5.62 cm) with 10 lesions being T1a and one lesion T1b. Tissue sampling was done in 9/11 patients, 3 were papillary RCC and the rest, clear cell RCC. In two patients, the tumor was completely endophytic, three patients had partially endophytic tumors while 6 patients had exophytic lesions. The median nephrometry score was 6 (range: 4–11, Mode 4). Technical success was achieved in all patients. Complete response was achieved in 81% (9/11) of the patients at 1-month follow-up. Median follow-up period was 6 months. Two patients showed residual disease on follow-up imaging at 1 and 3 months, respectively.

Conclusion Cryoablation is a promising, relatively new minimally invasive therapy for treating small renal tumors in India. It is safe, technically feasible, and shows excellent short-term efficacy.

Keywords

cryoablation - renal cell carcinoma - ablation

Financial Disclosure

None.




Publication History

Article published online:
11 January 2022

© 2022. Indian Society of Vascular and Interventional Radiology. This is an open access article published by Thieme under the terms of the Creative Commons Attribution-NonDerivative-NonCommercial License, permitting copying and reproduction so long as the original work is given appropriate credit. Contents may not be used for commercial purposes, or adapted, remixed, transformed or built upon. (https://creativecommons.org/licenses/by-nc-nd/4.0/)

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