Urinuntersuchung – Schritt für Schritt

Abstract

The examination of the urine is the oldest and a very basic technique for every nephrologist. It helps to detect, diagnose and classify diseases of the kidneys and the urinary tract. Proteinuria is an important sign of kidney disease and an own factor in the pathophysiology of renal progression. Acanthocytes in the urine (> 5 %) have a high specifity (98 – 100 %) for diagnosing a glomerular hematuria.

Die Urinuntersuchung ist zwar die älteste Methode, um Erkrankungen der Nieren und der ableitenden Harnwege zu erkennen. Sie hat aber immer noch einen zentralen Stellenwert in der Diagnostik von Nierenerkrankungen [1] [2].

Schlüsselwörter

Urinsediment - Proteinurie - glomeruläre Hämaturie

Key words

urine sediment - proteinuria - glomerular hematuria

• Literatur

• 1 Fogazzi GB, Verdesca S, Garigali G. Urinalysis: core curriculum 2008. Am J Kidney Dis 2008; 51: 1052-1067
• 2 Eknoyan G. Looking at the urine: the renaissance of an unbroken tradition. Am J Kidney Dis 2007; 49: 865-872
• 3 Kouri TT, Gant VA, Fogazzi GB. et al. Towards European urinalysis guidelines. Introduction of a project under European Confederation of Laboratory Medicine. Clin Chim Acta 2000; 297: 305-311
• 4 Fogazzi GB, Grignani S. Urine microscopic analysis--an art abandoned by nephrologists?. Nephrol Dial Transplant 1998; 13: 2485-2487
• 5 Fogazzi GB, Garigali G. The clinical art and science of urine microscopy. Curr Opin Nephrol Hypertens 2003; 12: 625-632
• 6 Cohen RA, Brown RS. Clinical practice. Microscopic hematuria. N Engl J Med 2003; 348: 2330-2338
• 7 Kohler H, Wandel E, Brunck B. Acanthocyturia – a characteristic marker for glomerular bleeding. Kidney Int 1991; 40: 115-120
• 8 Kitamoto Y, Tomita M, Akamine M. et al. Differentiation of hematuria using a uniquely shaped red cell. Nephron 1993; 64: 32-36
• 9 Kimmel M, Shi J, Wasser C. et al. Urinary [TIMP-2]·[IGFBP7] – Novel Biomarkers to Predict Acute Kidney Injury. Am J Nephrol 2016; 43: 375-382
• 10 Kimmel M, Schanz M, Alscher MD. Risk prediction of acute kidney injury by [TIMP-2]·[IGFBP7]. Drugs Today (Barc) 2017; 53: 349-356
• 11 Becker GJ, Garigali G, Fogazzi GB. Advances in Urine Microscopy. Am J Kidney Dis 2016; 67: 954-964