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Synthesis 1985; 1985(6/7): 609-611
DOI: 10.1055/s-1985-34142
DOI: 10.1055/s-1985-34142
paper
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Monobactams: Stereoselective Synthesis of trans-3-Amino- and 3-Acylamino-4-trifluoromethyl-2-azetidinones
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Publication History
Publication Date:
18 September 2002 (online)
An improved synthesis of trans-3-amino-4-trifluoromethyl-2-azetidinone (7), a precursor of trans-4-trifluoromethyl monobactams such as 9 and 10, is described.