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Synthesis 1991; 1991(10): 883-884
DOI: 10.1055/s-1991-26600
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Synthese von 2(1H)-Pyridonen aus 2H-Pyran-2-onen

Vratislav Kvita*
  • *Zentrale Forschungslaboratorien, Ciba-Geigy AG, CH-4002 Basel, Switzerland
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Publication Date:
29 April 2002 (online)

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Synthesis of 2(1H)-Pyridones From 2H-Pyran-2-ones 5-Substituted and 4,5-disubstituted 2(1H)-pyridones (13 examples) with formyl, acyl, alkoxycarbonyl, and trifluoromethyl groups in the 5 position were prepared in 16-97% yield by amination of the corresponding 2H-pyran-2-ones with hexamethyldisilazane or alkyl(trimethylsilyl)amines.