Download PDF
Synlett 1992; 1992(3): 211-213
DOI: 10.1055/s-1992-21316
letter
© Georg Thieme Verlag, Rüdigerstr. 14, 70469 Stuttgart, Germany. All rights reserved. This journal, including all individual contributions and illustrations published therein, is legally protected by copyright for the duration of the copyright period. Any use, exploitation or commercialization outside the narrow limits set by copyright legislation, without the publisher's consent, is illegal and liable to criminal prosecution. This applies in particular to photostat reproduction, copying, cyclostyling, mimeographing or duplication of any kind, translating, preparation of microfilms, and electronic data processing and storage.

A Model for the Stereoselectivity of Radical Mediated Reductive Alkylation of Acyclic Enamines

Philippe Renaud* , Peter Björup, Pierre-Alain Carrupt, Kurt Schenk, Serge Schubert
  • *Institut de Chimie Organique, 2 rue de la Barre, Université de Lausanne, CH-1005 Lausanne, Switzerland
Further Information

Publication History

Publication Date:
08 March 2002 (online)

  PDF Download  Permissions and Reprints All articles of this category

The radical mediated reductive alkylation of enamines [e.g., (E)-1-phenyl-1-pyrrolidino-1-propene (1)] derived from propiophenone is investigated. The observed stereoselectivities are explained with a model based on semiempirical calculations of the radical intermediate conformation.