Download PDF
Synlett 1994; 1994(3): 211-212
DOI: 10.1055/s-1994-22798
letter
© Georg Thieme Verlag, Rüdigerstr. 14, 70469 Stuttgart, Germany. All rights reserved. This journal, including all individual contributions and illustrations published therein, is legally protected by copyright for the duration of the copyright period. Any use, exploitation or commercialization outside the narrow limits set by copyright legislation, without the publisher's consent, is illegal and liable to criminal prosecution. This applies in particular to photostat reproduction, copying, cyclostyling, mimeographing or duplication of any kind, translating, preparation of microfilms, and electronic data processing and storage.

An Efficient, High-Yield Preparation of Substituted 2,2′-Bipyrroles

J. L. Sessler* , M. C. Hoehner
  • *Department of Chemistry and Biochemistry, University of Texas at Austin, Austin, Texas 78712, U.S.A
Further Information

Publication History

Publication Date:
22 March 2002 (online)

  PDF Download  Permissions and Reprints All articles of this category

An improved synthesis of alkyl substituted 2,2′-bipyrroles is described. It involves first pyrrolic nitrogen protection of substituted 2-iodopyrroles, then Ullmann-type coupling, followed finally by deprotection of the resulting 2,2′-bipyrroles. Using this procedure, yields of 2,2′-bipyrroles are typically enhanced by 20 to 30% depending on the pyrrole ring substitution and the scale of the reaction.