Download PDF
Synlett 1994; 1994(7): 524-526
DOI: 10.1055/s-1994-22914
letter
© Georg Thieme Verlag, Rüdigerstr. 14, 70469 Stuttgart, Germany. All rights reserved. This journal, including all individual contributions and illustrations published therein, is legally protected by copyright for the duration of the copyright period. Any use, exploitation or commercialization outside the narrow limits set by copyright legislation, without the publisher's consent, is illegal and liable to criminal prosecution. This applies in particular to photostat reproduction, copying, cyclostyling, mimeographing or duplication of any kind, translating, preparation of microfilms, and electronic data processing and storage.

Synthesis of 3-substituted but-3-enoic Acids via Palladium Catalysed Cross-Coupling Reaction of 3-iodobut-3-enoic Acid with Organometallic Reagents

Alain Duchêne* , Mohamed Abarbri, Jean-Luc Parrain, Masato Kitamura, Ryoji Noyori
  • *Laboratoire de Synthèse et d'Etudes Physicochimiques Organiques, Faculté des Sciences de Tours, Parc de Grandmont, 37200 Tours (France)
Further Information

Publication History

Publication Date:
18 September 2002 (online)

  PDF Download  Permissions and Reprints All articles of this category

3-Substituted but-3-enoic acids can be obtained in good yields under mild experimental conditions by palladium-catalysed cross-coupling of 3-iodobut-3-enoic acid with organozinc or organotin compounds using PdCl2(MeCN)2 as catalyst and DMF as solvent.