Download PDF
Synthesis 1994; 1994(8): 775-776
DOI: 10.1055/s-1994-25569
short paper
© Georg Thieme Verlag, Rüdigerstr. 14, 70469 Stuttgart, Germany. All rights reserved. This journal, including all individual contributions and illustrations published therein, is legally protected by copyright for the duration of the copyright period. Any use, exploitation or commercialization outside the narrow limits set by copyright legislation, without the publisher's consent, is illegal and liable to criminal prosecution. This applies in particular to photostat reproduction, copying, cyclostyling, mimeographing or duplication of any kind, translating, preparation of microfilms, and electronic data processing and storage.

Synthesis of Substituted N-Arylpiperidines via Organobismuth Derivatives

Aldo Banfi* , Marcella Bartoletti, Elio Bellora, Maura Bignotti, Marco Turconi
  • *Boehringer Ingelheim Italia S.p.A., Medicinal Chemistry Department, Via Serio 15, I-20139 Milano, Italy
Further Information

Publication History

Publication Date:
17 September 2002 (online)

  PDF Download  Permissions and Reprints All articles of this category

The synthesis of N-arylpiperidines functionalized both on the aromatic and piperidine ring was performed using conveniently substituted triarylbismuthine derivatives as arylating agents. This method is, in particular, indicated to arylate the nitrogen atom of a secondary amine with a phenyl ring bearing electron-withdrawing groups in the m-position.