Download PDF
Synthesis 1995; 1995(8): 926-928
DOI: 10.1055/s-1995-4044
short paper
© Georg Thieme Verlag, Rüdigerstr. 14, 70469 Stuttgart, Germany. All rights reserved. This journal, including all individual contributions and illustrations published therein, is legally protected by copyright for the duration of the copyright period. Any use, exploitation or commercialization outside the narrow limits set by copyright legislation, without the publisher's consent, is illegal and liable to criminal prosecution. This applies in particular to photostat reproduction, copying, cyclostyling, mimeographing or duplication of any kind, translating, preparation of microfilms, and electronic data processing and storage.

Aromatic Iodination of Activated Arenes and Heterocycles with Lead Tetraacetate as the Oxidant

Barbara Krassowska-Řwiebocka, Piotr Luliński, Lech Skulski*
  • *Chair and Laboratory of Organic Chemistry, Department of Pharmacy, Medical Academy, Banacha 1, PL 02-097 Warsaw, Poland, Fax +48(22)231487
Further Information

Publication History

Publication Date:
31 December 2000 (online)

  PDF Download  Permissions and Reprints All articles of this category

An easy, cheap and fairly quick laboratory method is presented for aromatic iodination of some highly activated arenes and heterocycles with molecular iodine in the presence of either pure lead tetraacetate dissolved in glacial acetic acid, or with the same oxidant but prepared in situ from Pb3O4 dissolved in hot AcOH/Ac2O prior to the iodination. 4-Bromo- and 2,4-dibromoanisoles are obtained from anisole by the respective oxidative bromination.

Lead tetraacetate as oxidant in aromatic iodination of activated arenes and heterocycles