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Synlett 1996; 1996(9): 922-924
DOI: 10.1055/s-1996-5618
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Enantiotopical Synthesis of Carbazoquinocins A and D, The Potent Lipid Peroxidation Inhibitors from Streptomyces violaceus 2448-SVT2

Kogyoku Shin, Kunio Ogasawara*
  • *Pharmaceutical Institute, Tohoku University, Aobayama, Sendai 980-77, Japan, Fax +81-22-217-6845; E-mail c21799@cctu.cc.tohoku.ac.jp
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Publication Date:
31 December 2000 (online)

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Carbazoquinocins A and D, the potent lipid peroxidation inhibitors isolated from Streptomyces violaceus, have been synthesized for the first time in a chiral way. The synthesis has led us to presume the absolute configuration of natural carbazoquinocin A as S.

enantiotopical synthesis - carbazoquinocins - configuration of carbazoquinocin A - lipid peroxidation inhibitor - chiral O-benzylglycidol