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Synlett 1999; 1999(9): 1483-1485
DOI: 10.1055/s-1999-2850
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Synthesis of (2-Deoxy-2-Fluoro-Glycosyl)Amino-Acids

M. Albert* , B. J. Paul, K. Dax
  • *Institute of Organic Chemistry, Graz University of Technology, Stremayrgasse 16, A-8010 Graz, Austria; Phone + 43 316 8 73 87 44; Fax +43 316 8 73 87 40; E-mail: dax@orgc.tu-graz.ac.at
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Publication Date:
31 December 1999 (online)

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Syntheses of various (2-deoxy-2-fluoro-glycosyl)amino-acids are described. This new class of acid stable glycoconjugates was accessible by electrophilic fluorination of glycals, followed by coupling with suitable protected serine and aspartic acid derivates.

electrophilic fluorination - 2-deoxy-2-fluoro sugars - glycoconjugates - N- and O-glycosyl-amino acids