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Synlett 1999; 1999(10): 1594-1596
DOI: 10.1055/s-1999-2900
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Synthesis of Novel Indole Derivatives: Variations in the Bartoli Reaction

Adrian P. Dobbs* , Martyn Voyle, Neil Whittall
  • *SmithKline Beecham Pharmaceuticals, Old Powder Mills, Leigh, Tonbridge, Kent TN11 9AN, UK; E-mail: adrian@apdobbs.demon.co.uk; Neil_Whittall-1@sbphrd.com
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Publication Date:
31 December 1999 (online)

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The synthesis of a range of novel substituted indoles and tricyclic indole derivatives is described using an extension of the Bartoli methodology.

Grignard reactions - indoles - Bartoli reaction - regioselectivity