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Synlett 2000; 2000(1): 75-76
DOI: 10.1055/s-2000-6449
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Microwave-Assisted Synthesis of Substituted Pyrroles by a Three-Component Coupling of α,β-Unsaturated Carbonyl Compounds, Amines and Nitroalkanes on the Surface of Silica Gel

Brindaban C. Ranu* , Alakananda Hajra, Umasish Jana
  • *Department of Organic Chemistry, Indian Association for the Cultivation of Science, Jadavpur, Calcutta, 700 032, India
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Publication Date:
31 December 2000 (online)

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An improved procedure has been developed for the synthesis of highly substituted pyrroles through a simple one-pot reaction of α,β-unsaturated aldehydes/ketones, amines and nitroalkanes on the surface of silica gel without any solvent undermicrowave irradiation.

substituted pyrrole - three-component coupling - microwave - silica gel