Download PDF
Synlett 2000; 2000(1): 128-130
DOI: 10.1055/s-2000-6473
letter
© Georg Thieme Verlag, Rüdigerstr. 14, 70469 Stuttgart, Germany. All rights reserved. This journal, including all individual contributions and illustrations published therein, is legally protected by copyright for the duration of the copyright period. Any use, exploitation or commercialization outside the narrow limits set by copyright legislation, without the publisher's consent, is illegal and liable to criminal prosecution. This applies in particular to photostat reproduction, copying, cyclostyling, mimeographing or duplication of any kind, translating, preparation of microfilms, and electronic data processing and storage.

Radical Reaction of Phenylsulfonyl Oxime Ethers on Solid Support: Application to the Synthesis of α-Amino Esters

Gee-Ho Jeon* , Joo-Yong Yoon, Sunggak Kim, Sung Soo Kim
  • *Center for Molecular Design and Synthesis and Department of Chemistry, Korea Advanced Institute of Science and Technology, Taejon 305-701, Korea; E-mail: skim@sorak.kaist.ac.kr
Further Information

Publication History

Publication Date:
31 December 2000 (online)

  PDF Download  Permissions and Reprints All articles of this category

Radical reaction of alkyl iodides with resin-bound phenylsulfonyl oxime ether 1 and hexamethylditin in benzene at 300 nm for 24 h followed by cleavage of support and the subsequent reduction of oxime ethers 3 with 10% Pd on carbon afforded α-amino esters 6 in reasonable yields.

free radical acylation - solid phase synthesis - phenylsulfonyl methoxy carbonyl oxime ether - α-amino esters