Int J Sports Med 2000; 21(7): 480-484
DOI: 10.1055/s-2000-7422
Physiology and Biochemistry
Georg Thieme Verlag Stuttgart · New York

Effects of Acute Ingestion of Salbutamol During Submaximal Exercise

K. Collomp1, 2 ,  R. Candau3 ,  R. Collomp4 ,  J. Carra3 ,  F. Lasne1 ,  C. Préfaut5 ,  J. De Ceaurriz1
  • 1 Laboratoire National de Dépistage du Dopage, Chatenay-Malabry, France
  • 2 EA 1609, Division STAPS, UFR Scientifique d'Orsay, Orsay, France
  • 3 JE 147, Faculté des Sciences du Sport, Montpellier, France
  • 4 Pharmacie centrale, CHU L'Archer, Nice, France
  • 5 Service Central de Physiologie Clinique, Hôpital A. de Villeneuve, Montpellier, France
Weitere Informationen

Publikationsverlauf

Publikationsdatum:
31. Dezember 2000 (online)

Preview

To assess the eventual effects of acute oral salbutamol intake on performance and metabolism during submaximal exercise, nine healthy volunteers completed two cycling trials at a power corresponding to 80 - 85 % V˙O2max, after either placebo (Pla) or salbutamol (Sal, 6 mg) treatment, according to a double-blind randomized protocol. Blood samples were collected both at rest and during exercise (5 min-, 10 min-, 15 min-exhaustion) for C-peptide, FFA, lactate and blood glucose measurements. Cycling performance was significantly improved in the Sal vs. Pla trials (p < 0.05). After Sal intake, resting C-peptide, lactate, FFA and blood glucose values were higher whereas exercise lactate and free fatty acid concentrations were greater during and at the conclusion of the exercise period (p < 0.05). These results suggest that acute salbutamol ingestion improved performance during submaximal exercise probably through an enhancement of the overall contribution to energy production from both aerobic and anaerobic metabolisms.

References

Katia Collomp

Laboratoire National de Dépistage du Dopage CREPS

143, Av Roger Salengro 92290 Chatenay-Malabry France

Telefon: Phone:+ 33 (1) 46602869

Fax: Fax:+ 33 (1) 46603017

eMail: E-mail:katia.collomp@staps.u-psud.fr