Development and Synthesis of an Arylboronic Acid-based Solid-Phase Amidation Catalyst

Abstract

A polystyrene-bound pyridineboronic acid was synthesized and shown to be an efficient, easily recoverable and reusable amidation catalyst.

Key words

arylboronic acid - amidation - catalyst - solid-phase - recoverable

References

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9

Aldrich Chemical Catalogue 2000-2001, 1045 FT NMR 1(2).

11

Aldrich Chemical Catalogue 2000-2001, 1088 FT NMR 1(2).

12

All amides were characterized by ¹H NMR spectroscopy and match previously reported data or ¹H NMR data of the corresponding amide prepared by DCC activation.

13

Percent loading of the solid-phase resin was determined by boron and nitrogen elemental analysis.